Organonitrogen Compounds
Medchemexpress LLC RIPK3-IN-1 | 2361139-70-8 | 99.3% | 100 MG
RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. It inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 μM, respectively. It also acts as a c-Met kinase inhibitor with an IC50 of 1.1 μM. In vitro, RIPK3-IN-1 also inhibits ABL, BRAF/V599E, MAP4K3, and SRC with IC50s of 0.37, 0.15, 0.012, and 0.075 μM, respectively.
- Inhibits RIPK3 with high potency
- Targets RIPK1 and RIPK2
- Acts as a c-Met kinase inhibitor
- Exhibits additional inhibitory activity against ABL, BRAF/V599E, MAP4K3, and SRC
- Useful for studying necroptosis, a programmed form of cell death
- Relevant for research into various diseases including ischemia reperfusion injury, neurodegenerative disorders, pancreatic cancer, and autoimmune diseases like inflammatory bowel disease (IBD)
Medchemexpress LLC Creatine Kinase (CPK/CK), Bovine Heart (CK, CPK, Creatine Phosphokinase) | 9001-15-4 | 10 KU
Creatine Kinase (CPK/CK), Bovine Heart, also identified as CK, CPK, or Creatine Phosphokinase, is a biological material or organic compound specifically designed for life science research. This product is intended solely for research applications and is not available for patient use.
- Suitable for life science research applications.
- Provided as a biological material or organic compound.
Sigma Aldrich Fine Chemicals Biosciences Clonidine hydrochloride so1G
Clonidine hydrochloride has antihypertensive analgesic and antidiarrheal properties. It lowers short-circuit current blocks anion secretion improves mucosal absorption of fluids and electrolytes in vitro. Clonidine is used to treat attention deficit and hyperactivity disorders (ADHD) menopausal flushing drug withdrawal and Tourette syndrome.
Medchemexpress LLC Ser-(2,3-Bispalmitoyloxypropyl)-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe | 322455-70-9 | 99.2% | 1666.16 | 1 MG
FSL-1 is a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist that enhances resistance to experimental HSV-2 infection. It significantly reduces HSV-2 replication in vitro and in human vaginal epithelial cells, and induces resistance to experimental genital HSV-2 infection via a specific cytokine response. FSL-1 also enhances phagocytosis of bacteria by macrophages through a Toll-like receptor 2-mediated signaling pathway.
- Enhances resistance to experimental HSV-2 infection.
- Reduces HSV-2 replication in vitro and in human vaginal epithelial cells.
- Induces resistance to genital HSV-2 infection through specific cytokine response.
- Enhances phagocytosis of bacteria by macrophages.
- Functions as a TLR2/6 agonist.
eMolecules Chem-Impex Guanidine hydrochloride 5kg 342450117 29914 0 000 50-01-1 MFCD00013026 95 530 CH6ClN3
Chem-Impex Guanidine hydrochloride 5kg 342450117 29914 0 000 50-01-1 MFCD00013026 95 530 CH6ClN3
Chem-Impex International, Inc. Chloro-dipyrrolidinocarbenium hexafluorophosphate | MFCD00191333 | 100G
Chloro-dipyrrolidinocarbenium hexafluorophosphate, MFCD00191333, 100G
Medchemexpress LLC Creatine kinase M-type (CKM) protein, human (N-His tag) | 9001-15-4 | >95.0% | 10 UG
Recombinant human creatine kinase M-type (CKM) protein with an N-terminal His tag, expressed in E. coli and supplied as a purified, biologically active enzyme for research use. The protein is approximately 45 kDa, available in microgram quantities, and characterized for activity and purity (>95% by reducing SDS-PAGE). Intended for biochemical assays, enzyme activity studies, and antibody validation; not for clinical or diagnostic use.
- Recombinant human CKM with N-terminal His tag.
- Expressed in E. coli for high-yield production.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Biologically active and suitable for enzymatic assays.
- Supplied in microgram quantities for small-scale experiments.
- Datasheet and COA provided for lot-specific quality information.
Medchemexpress LLC Allantoin (Standard) | 97-59-6 | MFCD00005260 | 158.12 | 25 MG
Allantoin (Standard) is the analytical standard of Allantoin, intended for research and analytical applications. It acts as a skin conditioning agent, promoting healthy skin and stimulating new, healthy tissue growth. This compound is typically used as an analytical standard for assays and in qualitative, quantitative, and methodological research experiments.
- Promotes healthy skin
- Stimulates new and healthy tissue growth
- Used in HPLC, GC, and MS research experiments
- Reference for assays
eMolecules Guanidine sulfate | 594-14-9 | MFCD00013115 | 25g
Combi-Blocks, Inc. | Guanidine sulfate | 25g | 603137217 | QC-2770 | 95.000 | 594-14-9 | MFCD00013115 | 216.220 | C2H12N6O4S
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Sigma Aldrich Fine Chemicals Biosciences Nalpha Tosyl L lysne chlo500MG
Nalpha Tosyl L lysne chlo500MG
![eMolecules Pharmablock / 5H6H7H-cyclopenta[b]pyridin-5-ol / 25mg / 717426504 / PBWB100461 / 0.000 / 1065609-70-2 / MFCD09800610 / 135.166 / C8H9NO](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502514481.JPG-250.jpg)
eMolecules Pharmablock / 5H6H7H-cyclopenta[b]pyridin-5-ol / 25mg / 717426504 / PBWB100461 / 0.000 / 1065609-70-2 / MFCD09800610 / 135.166 / C8H9NO
Pharmablock / 5H6H7H-cyclopenta[b]pyridin-5-ol / 25mg / 717426504 / PBWB100461 / 0.000 / 1065609-70-2 / MFCD09800610 / 135.166 / C8H9NO
TARGETMOL CHEMICALS INC COPTISINE CHLORIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells and completely absorbed compounds. purity: 99%
![Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000243800.png-250.jpg)
Medchemexpress LLC Pyrrolo[3,4-b]pyrrole-5(1H)-carboxamide, N-[4-[(3-ethynylphenyl)amino]-7-methoxy-6-quinazolinyl] | 1353644-70-8 | 99.7% | 442.51 g/mol | C25H26N6O2 | 25 MG
Theliatinib is a potent, ATP-competitive, orally active, and highly selective epidermal growth factor receptor (EGFR) inhibitor supplied as a research chemical for biochemical and cellular studies. It shows low-nanomolar potency against wild-type EGFR and measurable activity against clinically relevant mutant forms.
- Potent, ATP-competitive EGFR inhibitor with Ki = 0.05 nM and IC50 = 3 nM.
- Active against EGFR T790M/L858R mutant (IC50 ≈ 22 nM).
- High purity (~99.7%) suitable for biochemical and cellular assays.
- Molecular weight 442.51 g/mol; formula C25H26N6O2.
- Soluble in DMSO and supplied for laboratory research use only.
STA PHARMACEUTICAL US LLC ANA 2'-F U amidite | 1 g | CAS 1190089-70-3 | MDL MFCD15145421
ANA 2'-F U amidite is a Amidite reagent (Subcategory: ANA Series) sold by WuXi TIDES. Offered in 1 g. Store at -20 °C. SDS available for reference.
Specifications
- CAS: 1190089-70-3
- MDL: MFCD15145421
- InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N
- Molecular Weight: 748.789165161
- Molecular Formula: C39H46FN4O8P
- Purity: ≥98%
- Container Type: 60 mL Glass (Septum)
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 38.3 g
- Commodity Code: 29349990
- Country Of Origin: China
- IUPAC: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- SMILES: CC(N(P(O[C@H]1[C@@H]([C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)C4=CC=CC=C4)N5C(NC(C=C5)=O)=O)F)OCCC#N)C(C)C)C